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  • Flow Chemistry Reaches Manufacturing Milestone

    Flow Chemistry Reaches Manufacturing Milestone

    via c&en : Lilly chemists make chemotherapy drug candidate in a multistep continuous flow process using current Good Manufacturing Practices. Although continuous flow chemistry—wherein molecules are made in a continuous process rather than in batches—has gained ground in academic labs, its adoption by industry and contract manufacturing labs has been comparatively slow. Now, chemists at Eli Lilly & Co. report a continuous manufacturing process for the chemotherapy drug candidate prexasertib monolactate monohydrate. Notably, the synthesis uses […]

  • Genetic engineering through click chemistry

    Genetic engineering through click chemistry

    Via C&EN : Gene therapy and a range of biological research rely on the efficient delivery of nucleic acids into cells through the process known as transfection. Most widely-used transfection approaches for mammalian cells rely on electrostatic forces, usually taking advantage of cationic reagents to bind to negatively-charged nucleic acids and form strong ionic complexes. Cells then grab these complexes and internalize them through a process called endocytosis. However, the concentration of positive charge in the […]

  • The science of songs: how does music affect your body chemistry?

    The science of songs: how does music affect your body chemistry?

    Via The Guardian : Classical music makes shoppers buy more. Gentle tunes can cure insomnia. How? Writer, composer and science lecturer John Powell explains. Like many music lovers I’ve always had a fascination with the emotional power. How can a combination of sounds make all the hairs on your arms stand on end, or make you cry? I’ve always enjoyed reading newspaper and magazine articles about the psychological effects of music, but apart from the general […]

  • Smart chemistry is everywhere in everyday life

    Smart chemistry is everywhere in everyday life

    Via Albany Business Review : If you’re like many people, when you think of chemistry one of two images pops into your head: visions of the periodic table from your high school chemistry class or images of labs and beakers, microscopes and white coats. It may feel like chemistry is worlds away from your present daily life, but what you may not realize is the significance of chemistry and its impact all around you. Chemistry improves […]

  • A leap in Chemistry

    A leap in Chemistry

    Via Deccan Chronicle : Arabinda Chaudhuri, who was selected as a Fellow of Royal Society of Chemistry, UK, talks about the power of science. Hyderabad-based scientist, Dr Arabinda Chaudhuri, has been elected as a Fellow of Royal Society of Chemistry (FRSC) in the United Kingdom, and will work with other eminent scientists in advancing chemical sciences. Dr Arabinda, who is the Chief Scientist, Department of Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad, has published his […]

  • Senior Research Fellow Juan Perez-Mercader has published work on the development of an artificial proto-cell that self-assembles, grows, replicates, and moves toward light.

Jon Chase/Harvard Staff Photographer

    Mimicking life in a chemical soup

    Via Harvard Gazette : Researcher’s work revealing ‘phoenix vesicles’ builds on mathematical models A Harvard researcher seeking a model for the earliest cells has created a system that self-assembles from a chemical soup into cell-like structures that grow, move in response to light, replicate when destroyed, and exhibit signs of rudimentary evolutionary selection. While the system, developed by senior research fellow Juan Pérez-Mercader, mimics what one might conceive of as early cell behavior, a major caveat […]

  • The chemistry of chocolate

    The chemistry of chocolate

    Via Varsity : Zi Ran Shen explores the sweet taste of crystallography Those who know me well have often been treated to my impassioned speech about how overwhelmingly sweet chocolates are. I’ve often refused chocolate desserts, ice-cream, and confectionery, citing my boredom with their overuse while choosing their fruity counterpart. Though my culinary experience with them has been less than thrilling, my scientific relationship with this substance is nothing short of magical. As anyone that has […]

  • Sulfur linkage takes click chemistry in a different direction

    Sulfur linkage takes click chemistry in a different direction

    Via Chemistry World : Thionyl tetrafluoride-based ‘sleeping beauties’ enable click chemistry in a tetrahedral shape Nobel laureate Barry Sharpless and his collaborators have smashed together two storybook-nicknamed scientific worlds, calling on ‘sleeping beauty’ chemical groups to break his famous click chemistry out of ‘flatland’. The original click chemistry – clean, copper-catalysed triazole formation developed by Sharpless’ team at Scripps Research Institute in San Diego, US – has many uses today, including tagging biomolecules. However, the chemical […]

  • Chemistry offers students a bright future, Australia’s chief scientist says

    Chemistry offers students a bright future, Australia’s chief scientist says

    Via The Guardian : Alan Finkel says it is time to put ‘flesh on the bones’ of the country’s national research priorities and harness ‘this science for a better life’ Australia’s chief scientist, Alan Finkel, has said it is time to put “flesh on the bones” of the country’s national science and research priorities, and to highlight to government areas of opportunity in science. In a speech to launch the Australian Academy of Science’s decadal plan […]

  • What does chemistry mean to you?

    What does chemistry mean to you?

    Via LinkedIn : The meaning of chemistry to one person and the next could be entirely different. It is a matter of that person’s immediate perceptions when the words chemist, chemistry and chemicals are presented to them and based upon their understanding, experiences with and knowledge of chemistry. To one it could have little or no meaning but to another it could be understood as the way in which technology, medicine and other fields continually advance. […]